AGENDA |
| Tuesday, March 24, 2009 |
| 7:30 – 8:00 a.m. |
Registration |
| Welcome and Introduction |
| 8:00 – 8:20 a.m. |
Welcome and Introduction
Steve James |
| 8:20 – 8:40 a.m. |
Clinical Overview: Unmet Needs and Challenges
Pankaj J. Pasricha |
| 8:40 – 9:00 a.m. |
Clinical Overview: A Clinical Urologist’s View of Bladder Smooth Muscle Function
Steve Zderic |
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| Session 1: Structure and Contraction of Organ Smooth Muscle |
| 9:00 – 9:15 a.m. |
Session Overview
Karnam Murthy |
| 9:15 – 9:45 a.m. |
Myoarchitecture and Organ Function
Ravinder Mittal |
| 9:45 – 10:15 a.m. |
Potassium Channels and Smooth Muscle Function
Mark Nelson |
| 10:15 – 10:30 a.m. |
BREAK |
| 10:30 – 11:00 a.m. |
Signal Integration Through Myosin Phosphorylation in Smooth Muscle
James Stull |
| 11:00 – 11:30 a.m. |
Caldesmon and Actin-Based Regulation in Smooth Muscle Cells
C.-L. Albert Wang |
| 11:30 – 12:45 p.m. |
LUNCH (on your own) |
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| Session 2: Phenotypes and Functions of Smooth Muscle |
| 12:45 – 1:00 p.m. |
Session Overview
Don Powell |
| 1:00 – 1:30 p.m. |
Prostatic Smooth Muscle/Stromal Cells Normal Physiology and Disease
Karl-Erik Anderson |
| 1:30 – 2:00 p.m. |
Regulation and Function of the Inflammatory Vascular Smooth Muscle Cell Phenotype
Brian Wamhoff |
| 2:00 – 2:30 p.m. |
Myofibroblasts and Gut Epithelial Proliferation/Stem Cell Niche
Deborah Rubin |
| 2:30 – 3:00 p.m. |
Role of Cryptic Smooth Muscle and Myofibroblast Cells as Intestinal Stem Cell Niche
Xin Chen |
| 3:00 – 3:15 p.m. |
BREAK |
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| Session 3: Developmental Origins of Smooth Muscle and Interactions Leading to Differentiation |
| 3:15 – 3:30 p.m. |
Session Overview
Gary Owens |
| 3:30 – 4:00 p.m. |
Role of Hedgehog Signaling in Intestinal Smooth Muscle Development and Maintenance
Deborah Gumucio |
| 4:00 – 4:30 p.m. |
Epigenetic Regulation of Smooth Muscle Differentiation
Gary Owens |
| 4:30 – 5:00 p.m. |
What Is the Cellular Origin of the Bladder Trigone?
Cathy Mendelsohn |
| 5:00 – 5:30 p.m. |
Development, Function, and Plasticity of the Neuromuscular Apparatus in Visceral Smooth Muscles
Kenton Sanders |
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| Wednesday, March 25, 2009 |
| 7:30 – 8:00 a.m. |
Registration |
| Session 4: Effects of Inflammation and Disease on Structure and Function of Smooth Muscle; Potential for Therapy |
| 8:00 – 8:15 a.m. |
Session Overview
Gianrico Farrugia |
| 8:15 – 8:45 a.m. |
Obstruction-induced Alterations in the Contractile and Regulatory Proteins in the Bladder Wall Smooth Muscle
Sam Chacko |
| 8:45 – 9:15 a.m. |
Smooth Muscle and Interstitial Cells of Cajal in Diabetic Gastroenteropathy
Gianrico Farrugia |
| 9:15 – 9:45 a.m. |
Mechanisms of Immune Regulation of Gut Smooth Muscle Function
Terez Shea-Donohue |
| 9:45 – 10:00 a.m. |
BREAK |
| 10:00 – 10:30 a.m. |
Inflammation and Signaling in the Development of Esophagitis
Piero Biancani |
| 10:30 – 11:00 a.m. |
Gene Plasticity in Colonic Circular Smooth Muscle Cells Underlies Motility Dysfunction in a Model of Post-infective IBS
Sushil Sarna |
| 11:00 – 11:30 a.m. |
Regulation of Growth in Normal Intestinal Smooth Muscle and Dysregulation of Growth in the Inflamed Intestine
John Kuemmerle |
| 11:30 – 12:30 p.m. |
LUNCH |
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| Session 5: Regenerative Medicine |
| 12:30 – 12:45 p.m. |
Session Overview
Khalil Bitar |
| 12:45 – 1:15 p.m. |
Material Systems to Engineer Smooth Muscle
David Mooney |
| 1:15 – 1:45 p.m. |
Plasticity of Adult ICC Progenitors: Role in Turnover, Regeneration, and Neoplasia of the Gastrointestinal Musculature
Tamas Ordog |
| 1:45 – 2:00 p.m. |
BREAK |
| 2:00 – 2:30 p.m. |
De Novo Bladder Regeneration In Vivo: Regenerative Physiology/Pharmacology of Detrusor Smooth Muscle
George Christ |
| 2:30 – 3:00 p.m. |
Bioengineering of the Intestinal Smooth Muscle
James Dunn |
| 3:00 – 3:30 p.m. |
Aging and Bioengineering of Gastrointestinal Smooth Muscle Constructs
Khalil Bitar |
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| Session 6: Future Research Needs and Directions |
| 3:30 – 4:00 p.m. |
Future Research Needs and Directions
George Christ |
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