AGENDA
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5:00 – 7:00 p.m. |
Registration |
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7:00 – 9:00 p.m. |
Welcome Reception |
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7:00 a.m. |
Registration and Continental Breakfast |
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8:45 a.m. |
Opening Remarks
Robert Star, Director of the Division of Kidney, Urologic, and Hematologic Diseases (KUH)/NIDDK, USA |
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9:00 a.m. |
Session 1: Classical Regeneration Systems
Alejandro Sánchez Alvarado,  Howard Hughes Medical Institute and Stowers Institute for Medical Research, USA
Regeneration in Planaria
Panagiotis A. Tsonis, University of Dayton, Ohio, USA
Lens Regeneration in the Newt
Iswar Hariharan, University of California, Berkeley, USA
Imaginal Disc Regeneration in Drosophila |
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10:30 a.m. |
Moderator Discussion and Break |
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11:00 a.m. |
Session 2: Regeneration of Whole Organs in Vertebrates
Kenneth Chien, Massachusetts General Hospital/Harvard Medical School, USA
Driving Heart Progenitor Fate In Vivo With Modified mRNA
Michael Levin, Tufts University, USA
Bioelectrical Controls of Growth and Form: New Tools and Opportunities for Regenerative Medicine
John Stingl, University of Cambridge, UK
Cell Division Kinetics of Mouse Mammary Stem Cells
Gabrielle Kardon, University of Utah, USA
Regeneration of Vertebrate Skeletal Muscle |
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12:30 p.m. |
Moderator Discussion |
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12:45 p.m. |
Lunch |
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2:00 p.m. |
Session 3: What can Regenerative Medicine Learn from Cancer Growth?
Ralf Adams, Max Planck Institute for Molecular Biomedicine, Germany
Molecular Regulation of Angiogenic Sprouting
Jeff Pollard, Albert Einstein College of Medicine, USA
Monocyte and Macrophage Diversity Promotes Tumor Progression and Metastasis
Phillip Beachy, Stanford University, USA
Hh/Wnt Signaling Between Epithelium and Stroma in Bladder Regeneration
Raghu Kalluri, Harvard Medical School, USA
Stromal Regenerative Changes in Tumors
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4:00 p.m. |
Moderator Discussion and Break |
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4:30 p.m. |
Debate: Quiescent Progenitor Cells in Solid Organs: Do They Exist and Can They Be Harnessed to Regenerate Tissues?
Moderator: Robert Handin, Harvard Medical School, USA
Discussants: Panagiotis Tsonis, Alejandro Sánchez Alvarado, Raghu Kalluri, and
Neil Hukriede
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5:30 – 7:00 p.m. |
Poster Session
Banquet Dinner at Turf Valley |
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7:00 a.m. |
Registration and Continental Breakfast |
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8:00 a.m. |
Session 4: Vertebrate Developmental Pathways and Their Activation in Repair and Regeneration
Andrew McMahon, Harvard University, USA
Development, Damage, and Repair Responses in the Mammalian Kidney
Thaddeus Stappenbeck†, Washington University, USA
Monocytes in the Gut Stem Cell Niche and Regeneration
Mark Majesky, Seattle Children's Research Institute, USA
Vascular Stem/Progenitor Cells in the Aventitia of Blood Vessels |
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10:00 a.m. |
Moderator Discussion and Break |
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10:30 a.m. |
Session 5: Vascular Repair and Regeneration
Marty Friedlander, The Scripps Research Institute, USA
Mechanisms of Ocular Angiogenesis
Luisa Iruela-Arispe, University of California, Los Angeles, USA
Genetics of Blood Vessel Formation and Remodeling
Patricia D’Amore, Schepens Eye Research Institute, USA
The Role of Pericytes in Vessel Formation and Stability
George Davis, University of Missouri-Columbia, USA
Pericyte-regulated Vascular Tube Morphogenesis and Stabilization |
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12:30 p.m. |
Moderator Discussion |
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1:00 p.m. |
Lunch |
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2:00 p.m. |
Session 6: Resolution of Inflammation and Fibrosis
Charles Serhan, Harvard Medical School, USA
Can We Harness Natural Anti-Inflammatory & Pro-Resolving Mediators of Control Inflammation?
Adam Lacy-Hulbert, Harvard Medical School, USA
Apoptosis, Phagocytosis and TGF-beta: Harnessing Innate Immunity to Promote Repair
Scott Friedman, Mount Sinai School of Medicine, USA
Resolution of Fibrosis – Reality or a Dream? |
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3:30 p.m. |
Moderator Discussion and Break |
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4:00 p.m. |
Debate: What Are the Origins of Endothelial Progenitor Cells? And How Do We Define Them?
Moderators: Martin Friedlander and Luisa Iruela-Arispe
Discussants: Patricia D’Amore, George Davis, and Ralf Adams |
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5:00 – 6:00 p.m. |
Poster Session |
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6:00 – 7:15 p.m. |
Soccer Match |
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7:30 p.m. |
Dinner |
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7:00 – 8:00 a.m. |
Continental Breakfast |
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8:00 a.m. |
Session 7: Myeloid Cells in Repair/Regeneration
Richard Lang, Cincinnati Children’s Hospital, USA
Macophage Wnt Ligands in Development and Regeneration
Doug Losordo, Northwestern University, USA
Bone Marrow Progenitor Cell Recruitment to the Neovasculature
Jeremy Duffield, University of Washington, USA
Evidence for Developmental Pathways in Adult Kidney and Other Organ Repair |
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9:30 a.m. |
Moderator Discussion and Break |
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10:00 a.m. |
Session 8: Stem Cells, Telomeres and iPS Cells: Can We Modify Available Cells to Grow New Organ Units?
Calvin Kuo, Stanford University, USA
Role of Intestinal Stem/Progenitor Cells in Homeostasis and Repair
Jason Spence, University of Michigan Medical School, USA
Directed Differentiation of Human Pluripotent Stem Cells Into Intestinal Tissues In Vitro
Bruno Péault, University of California, Los Angeles, USA
Mesenchymal Stem Cells in Adult Human Organs: Identification, Purification, and Therapeutic Use
Steven Artandi, Stanford University, USA
Telomerase in Epithelial Regeneration and Stem Cell Self-Renewal
Final Discussion |
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12:00 – 1:30 p.m. |
Lunch |
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