DRAFT AGENDA

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Monday, April 12, 2010

7:00 a.m. – 8:00 a.m.	Registration, Poster Set-up, and Continental Breakfast

8:00 a.m. – 8:20 a.m.	Welcome Griffin Rodgers, Director, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Workshop Goals Ronald Margolis, NIDDK

Plenary 1 Genetics of Circadian Clocks in Mammals

8:20 a.m. – 9:00 a.m.	Joseph S. Takahashi, University of Texas Southwestern

Session 1: Central and Neural Circuitry

9:00 a.m. – 9:30 a.m.	Oscillators Entrained by Food and Metabolic Effects of “Anticipatory” Timing Rae Silver, Columbia University

9:30 a.m. – 10:00 a.m.	From Nodes to Networks in the Mammalian Circadian System Erik Herzog, Washington University

10:00 a.m. – 10:30 a.m.	Hypothalamic Circuitry Linking Feeding and Circadian Rhythms Clifford B. Saper, Harvard Medical School

10:30 a.m. – 10:50 a.m.	Break

Session 2: Model Organisms

10:50 a.m. – 11:20 a.m.	The Monarch Butterfly: The New Clock on the Block Steven Reppert, University of Massachusetts Medical School

11:20 a.m. – 11:50 a.m.	Circadian Rhythms in Drosophila Michael Rosbash, Brandeis University

11:50 a.m. – 12:20 p.m.	Interaction Between the Circadian Clock and Metabolism in Drosophila Amita Sehgal, University of Pennsylvania Medical School

12:20 p.m. – 1:30 p.m.	Lunch Break

Session 3: Transcription and Peripheral Clocks (I)

1:30 p.m. – 2:00 p.m.	Nuclear Receptors and AMPK – Resetting Metabolism Ronald M. Evans, Salk Institute

2:00 p.m. – 2:30 p.m.	Nuclear Receptor Regulation of Circadian Rhythm and Metabolism Mitchell Lazar, University of Pennsylvania

2:30 p.m. – 3:00 p.m.	The Impact of Circadian Misalignment on Cardiometabolic Function in Humans Steven Shea, Brigham and Women's Hospital

3:00 p.m. – 3:20 p.m.	Break

Session 4: Transcription and Peripheral Clocks (II)

3:20 p.m. – 3:50 p.m.	Circadian Oscillator and Metabolic Sand-Timer Determine Rhythmic Transcription in Liver Satchidananda Panda, Salk Institute

3:50 p.m. – 4:20 p.m.	Regulation of Circadian Rhythm by Ubiquitination Lei Yin, University of Michigan

4:20 p.m. – 4:50 p.m.	Circadian Post-transcriptional Regulation of Lipid Metabolism Carla B. Green, University of Texas Southwestern

4:50 p.m. – 5:05 p.m.	HOT TOPIC: Synthetic ROR and REV-ERB Ligands Modulate Lipid and Glucose Metabolism Thomas Burris, The Scripps Research Institute

5:05 p.m. – 5:20 p.m.	HOT TOPIC: Circadian Control of Beta Cell Function Vijay Yechoor, Baylor College of Medicine

5:20 p.m. – 7:00 p.m.	Poster Session

7:00 p.m.	Dinner (on your own)


Tuesday, April 13, 2010

7:00 a.m. – 8:00 a.m.	Registration and Continental Breakfast

Plenary 2 Signaling Within the Mammalian Circadian Timing System

8:00 a.m. – 8:40 a.m.	Ueli Schibler, University of Geneva

Session 5: Interplay Between the Clock and Physiology

8:40 a.m. – 9:10 a.m.	Metabolism and Circadian Clock: The Epigenetic Link Paolo Sassone-Corsi, University of California, Irvine

9:10 a.m. – 9:40 a.m.	The Tangled Web of Circadian and Metabolic Regulation John B. Hogenesch, University of Pennsylvania

9:40 a.m. – 10:10 a.m.	Molecular Pathophysiology of Diabetes and Obesity in Circadian Mutant Mice Joseph Bass, Northwestern University

10:10 a.m. – 10:30 a.m.	Break

10:30 a.m. – 11:00 a.m.	“Clocked” Up Arteries: Vascular Implications of the Circadian Clock R. Daniel Rudic, Medical College of Georgia

11:00 a.m. – 11:30 a.m.	Molecular Characterization of Human Sleep Variants Ying-Hui Fu, University of California, San Francisco

11:30 a.m. – 12:00 p.m.	Dysregulation of Sleep and Circadian Rhythms: Role in Obesity and Metabolic Disorders Fred Turek, Northwestern University

Session 6: Clocks and Human Disease

12:00 p.m. – 12:30 p.m.	Circadian Rhythm Disorders Charles A. Czeisler, Brigham and Women’s Hospital

12:30 p.m. – 1:00 p.m.	Human Circadian Variants and Insights Into Other Disorders Louis Ptacek, University of California, San Francisco

1:00 p.m. – 1:10 p.m.	Meeting Summary and Future Directions

1:10 p.m.	Adjournment