The objective of this workshop is to gain a better understanding of the link between circadian rhythms and human health and disease. A particular emphasis will be on the influence of both central and cellular clocks on the physiology of behavior and metabolism, specifically effects on overall energy balance and obesity. The neural circuitry underlying the central clock, the effects of environment and diet, and its impact on cellular clocks and gene regulation will be investigated. We are interested in the interrelationship between clock genes and genes involved in metabolism, both the impact of circadian rhythms on metabolic gene regulation as well as the effect of nutrient intake and balance on the molecular components of the clock. The impact of endocrine signaling, nuclear receptors, and growth factors on the regulation of clock genes will be addressed. Epigenetic mechanisms, specifically the role of clock genes in the modification of chromatin to influence gene regulation, will be discussed. Our aim is to bring together investigators that study circadian rhythms at all levels, neural, tissue specific, and cellular, as a means to gain a broader understanding of the role and impact of these rhythms on metabolism. The goal of this workshop is to identify areas of future research to better elucidate the contribution of circadian rhythms to metabolism and disease.

Poster Abstract Submission Deadline
Friday, February 19, 2010

Registration Deadline
Friday, March 19, 2010

ORGANIZERS:
Chuck Czeisler
Mitch Lazar
Ron Margolis
Sheryl Sato
Corinne Silva

FOR WORKSHOP CONTENT INFORMATION, CONTACT:
Corinne M. Silva, Ph.D.
Program Director
Intracellular and Intrauterine Signaling
DEM/NIDDK/NIH
Two Democracy Plaza, Room 794
6707 Democracy Boulevard
Bethesda, MD 20892-5460
Tel: (301) 451-7335
Fax: (301) 480-0475
E-mail: silvacm@mail.nih.gov

FOR REGISTRATION INFORMATION, CONTACT:
Denise Hoffman, CMP
Deputy Director of Conferences
The Scientifi c Consulting Group, Inc.
656 Quince Orchard Road, Suite 210
Gaithersburg, MD 20878-1409
Tel: (301) 670-4990 x232
Fax: (301) 670-3815
E-mail: dhoffman@scgcorp.com